Cancer cells acquire anoikis resistance via several mechanisms and signaling molecules including phosphoinositide 3‐kinase (PI3K)– protein kinase B (Akt) (144), Ras–extracellular signal regulated kinases (ERK) (145), Jun‐ N‐terminal kinase (146), mitogen‐activated protein–extracellular signal‐regulated kinase (147), and integrins (148). The gene discussed is AKT1; the disease is cancer.