Minimally required data to work properly include (1) preoperative tumor grade, (2) minimally three of four IHC markers (ER, PR, p53, or L1CAM), and (3) at least one clinical biomarker (CA 125 serum level, LN status according to imaging method, platelet count, or pap smear result) (7). Here, TP53 is linked to neoplasm.