As shown in Supplementary Table 2 and Supplementary Figure 1, patients with the MIP-predominant subtype exhibited a significantly worse DFS than those with other adenocarcinoma subtypes (P <0.05, Supplementary Figure 1A), and LEP and MIP subtypes exhibited the largest DFS difference, while SOL-predominant patients showed significantly worse OS (P <0.05, Supplementary Figure 1B). The gene discussed is LEP; the disease is adenocarcinoma.