PPP1R12A and malignant colon neoplasm: Circ-PPP1R12A encodes the conserved 73-aa small peptide PPP1R12A-C (but not circ-PPP1R12A itself), which promotes the proliferation, migration, and metastasis of colon cancer in vitro and in vivo by activating the Hippo/YAP signaling pathway (51).