FTH1 and pancreatic neoplasm: Although MMRi62 induces lysosomal degradation of ferritin heavy chain 1 (FTH1) and triggers ferroptosis in pancreatic cancer cells (46), FTH1 degradation is not involved in MMRi62-induced apoptosis in leukemia cells since MMRi67 induced the same level of FTH1 degradation as MMRi62 but without incurring apoptosis (Lama et al., unpublished data).