The top six anti-COVID-19 core targets, IL-6, PPARG, MAPK3, PTGS2, ICAM1, and MAPK1, were selected for molecular docking analyses with key active phytomolecules of Kochiae Fructus identified in section “Network of anti-COVID-19 targets and the Kochiae Fructus’s active phytomolecules.” The gene discussed is ICAM1; the disease is COVID-19.