IFIH1 and interstitial lung disease: In this study, we concluded that there was a significant correlation between ILD and anti-MDA5 antibody positivity (P = 0.012) and that patients with anti-MDA5 antibody-positive PM/DM were more likely to have comorbid ILD, but the difference of 3 deaths (16.7%) in the positive group versus 1 death (2.2%) in the negative group was not statistically significant based on the follow-up results.