GPT and Decreased total leukocyte count: In this sense, it is particularly significant that adult patients at the early stage of COVID-19 disease often have a remarkable decrease in their CD8+ and CD4+ T-cell subsets, leukopenia, and lymphopenia, alongside an elevation in their serum levels of liver enzymes (AST and ALT) and lactic dehydrogenase (LDH) [101, 102].