To validate the effect of SLC3A2 on cell proliferation, we analyzed the results from a large-scaled CRISPR-based screening in DepMap and found that the growth of around 95% cell-lines was partially dependent on SLC3A2 (Liu et al., 2022; Wiernicki et al., 2022), which supported the essential role of SLC3A2 in fueling cancer cell proliferation. Here, SLC3A2 is linked to cancer.