Moreover, since the role of IL-6 has been considered, by Osero et al., one of the greatest oxymora in the leishmaniasis outcome due to different studies showing discordant roles (Osero et al., 2020), this crosstalk also pointed toward the relevance that a module associated in this study to an LRV1 module may contribute to the leishmaniasis outcome. The gene discussed is IL6; the disease is leishmaniasis.