HSPA5 and pancreatic ductal adenocarcinoma: Heat shock protein family A [Hsp70] member 5 (HSPA5), an endoplasmic reticulum (ER)-sessile chaperone, has been documented as a ferroptosis suppressor in the Ferroptosis Database, which is in agreement with the result that HSPA5 negatively regulates ferroptosis in human pancreatic ductal adenocarcinoma cells (32).