For immune-related pathways, the riskscore was positively correlated with base excision repair, cell cycle, DNA replication, fanconi anemia pathway, homologous recombination, micRNAs in cancer, mismatch repair, nucleotide excision repair, oocyte meiosis, progesterone mediated oocyte maturation, pyrimidine metabolism, spliceosome and viral carcinogenesis, but positively correlated with IFN-gamma signature, APM signal and proteasome (Figure 5A). Here, IFNG is linked to cancer.