ABCC8 mutations can cause MODY in patients whose clinical features are similar to those with HNF1A/4AMODY (19), and some patients with ABCC8 mutations were able to change from insulin to oral glibenclamide therapy (21, 22), which means that patients with ABCC8presented with T2DM-like phenotypes. This evidence concerns the gene HNF1A and MODY.