The testosterone (T), luteinizing hormone (LH), insulin, and estradiol (E2) levels in the PCOS group were significantly higher than in the NS group (Figure 3A–C, 3E), and DOP/MET treatment was significantly reduced, while the serum FSH levels in the PCOS group were significantly lower than those in the NS group (Figure 3D), and DOP/MET treatment significantly increased the serum FSH level when compared to the PCOS group. This evidence concerns the gene PLOD1 and polycystic ovary syndrome.