β-sitosterol for 30 days interestingly reduced hyperglycemia and dyslipidemia as well as IR in adipocytes over the stimulation of insulin metabolic signaling (IRS-1/Akt/GLUT4) and inflammatory signaling molecules (IKKβ/NFkB and JNK) in adipose tissue [11–13]. This evidence concerns the gene INS and Hyperglycemia.