BCL2 and acute kidney injury: In mice with acute kidney injury (AKI) induced by ischemia/reperfusion injury (IRI), Li et al. showed that taraxasterol (5 and 10 mg/kg) inhibited mitochondrial ROS production and ameliorated apoptosis in the kidney by decreasing Bax expression and increasing Bcl2 expression (Li C. et al., 2020).