CHEK1 and colorectal cancer: Subsequently, the genes related to the IL-17 pathway, IL-6 pathway, apoptosis, and colorectal cancer metastasis in DEGs were extracted and plotted with a heat map (Figure 5C), which showed that CQF restricted the transcript levels of genes associated with inflammation (Il17A, Jun, Mmp9, Rela, Ccl2, Cxcl1, etc.), apoptosis (Rela, Fgfr1, Il1a, Chek1, Casp6, etc.)and colorectal cancer metastasis (Mmp7, Mmp9, Lef1, Axin2, Wnt11, Tcf4, Mmp12, Mmp14, Mmp2, etc.).