GPT and fibrosis: One study from the US reported that ferritin could distinguish significant fibrosis (F2–F4), advanced fibrosis (F3–F4) and cirrhosis (F4) from less severe fibrosis; the associations remained significant when age, gender and race were adjusted, yet became non-significant when more variables were included, e.g., BMI, medical history of diabetes, waist circumference, laboratory analysis results including alanine aminotransferase (ALT), etc. (53).