Additionally, one of the SNPs identified in the 3-way GMDR 0.9 analysis, MMP2.rs11639960, is an eQTL, affecting the expression levels of the gene called LPCAT2. LPCAT2 is known to affect response to chemotherapy in colorectal cancer patients through an association with lipid droplet formation (Cotte et al., 2018). The gene discussed is MMP2; the disease is colorectal cancer.