In pan-cancer prognostic analysis, Kaplan-Meier survival curves revealed a significant association of upregulated ANLN expression with poor OS in ACC, BLCA, BRCA, KIRC, KIRP, LIHC, LUAD, mesothelioma (MESO), and PAAD; contrastingly, low ANLN expression was associated with poor OS in THYM (Figure 4B). This evidence concerns the gene ANLN and adrenal cortex carcinoma.