Table 2 contains the gene name and LASSO coefficient. We examined the immunohistochemistry expression of seven genes (CSNK2A2 was not identified) in normal human tissues and HCC tissues from the HPA database and discovered that the majority of genes were overexpressed in HCC tissues (Figures 4A–G). Thus, risk score formula was as followed:Risk Score=TOMM22 expression×0.373+MFN1 expression×0.310+PGAM5 expression×0.292+TOMM5 expression×0.181+SQSTM1 expression×0.156+OPTN expression×0.122+ATG12 expression×0.040+CSNK2A2 expression×0.034. Here, OPTN is linked to hepatocellular carcinoma.