Winnepenninckx et al. (2006) reported that KPNA2 is closely associated with poor prognosis and tumor progression in melanoma, which is consistent with our results. Yang et al. (2020) found that KPNA2 promotes proliferation, invasion and migration through NF-κB/p65 signaling pathways in melanoma cells. Here, KPNA2 is linked to neoplasm.