The expression of KPNA4 in prostate cancer was shown to promote metastasis through miR-708-KPNA4-TNF axes (Yang et al., 2017), and KPNA4 was found to enhance cancer cell proliferation and cisplatin resistance in cutaneous squamous cell carcinoma (Zhang et al., 2019). The gene discussed is KPNA4; the disease is cutaneous squamous cell carcinoma.