He had unique metadiaphyseal splaying and osteosclerosis, vertebral end‐plate osteosclerosis, and cortical thinning of long bones but no mutation was detected of SLC29A3, TNFRSF11A, TCIRG1, LRRK1, or CSF1R associated with DSS. The gene discussed is TNFRSF11A; the disease is osteosclerosis.