It was found that the CD3+ level during the onset of the disease was comparable to that of asthma and healthy children, while CD4+ level and CD4+/CD8+ value increased significantly, and CD8+ level was in a state of decline, which was similar to the results of Miao Q et al.10, suggesting that the number and function of T lymphocyte subsets in children with bronchial asthma accompanied by recurrent infection are in a state of dysfunction, and the number of T helper cells is dominant, while the number of inhibitory T cells is significantly less. The gene discussed is CD8A; the disease is asthma.