Despite the use of PTX and CP in both groups, the observation group achieved better clinical efficacy as HIPEC at 42°C mediated the optimal efficacy of CP, induced cancer cell apoptosis directly, enhanced the membrane permeability of cancer cells and increased the PTX concentration in cancer cells.7 This procedure was performed directly in the abdominal cavity, which substantially strengthened the effect of eradicating residual cancer cells and foci after CRS. The gene discussed is CP; the disease is cancer.