In addition, RNA expression of FOXO1 and PPARG in clinical specimens were detected using RT-qPCR, confirming that hsa_circ_0002722-miR-130a/b-3p-PPARG and hsa_circ_0001837/hsa_circ_0000941-miR-135a/b-5p-FOXO1 were associated with the pathogenesis of AAA (Figures 8E,F). This evidence concerns the gene FOXO1 and triple-A syndrome.