SLC2A1 and ischemia: Whereas GLUT-1 is considered responsible for basal intracellular glucose transport, GLUT-4 and to a lesser extent GLUT-1 translocate to the plasma membrane and increase intracellular glucose uptake in response to stimuli such as insulin (21), ischemia (22, 23), anoxia (24), and catecholamines (20).