PIK3CA and hepatitis B virus infection: P. vulgaris was mainly involved in the PI3K-Akt signaling pathway (hsa04151, n = 30), MAPK signaling pathway (hsa04010, n = 29), hepatitis B (hsa05161, n = 32), human cytomegalovirus infection (hsa05163, n = 31), and the signaling pathway of the diabetes in the complication of diabetes mellitus.