Among these 5 hub genes, we found the expressions of COL1A1 [HR= 0.72 (0.58–0.91), P=0.005], COL3A1 [HR= 1.28 (1.02–1.6), P=0.031], and POSTN (HR= 0.75 (0.6–0.94), P=0.031) were significantly correlated with overall survival of BC patients (Figure 4), while the expressions of LUM [HR= 0.82 (0.66–1.03), P=0.084] and COL5A2 [HR= 0.95 (0.76–1.19), P=0.66] were not. Here, LUM is linked to breast cancer.