We have reported that a miR-150 antagonist reversed SOCS1/Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway in co-cultures of human kidney 2 (HK-2) cells and macrophages, and we further showed that LNA-anti-miR-150 alleviates folic acid-induced renal fibrosis in mice (12). The gene discussed is SOCS1; the disease is renal fibrosis.