Further dimensionality reduction clustering revealed that T cells were subdivided into six cell types, including naïve T cells, CD4+ effector memory T cells, CD8+ effector T cells, CD8+ mucosal-associated invariant T cells, CD4+ regulatory T cells, and proliferating T cells, of which the proportion of CD8+ effector T cells was predominant in keloids. The gene discussed is CD4; the disease is keloid.