Fibroblasts in keloids may specifically interact with macrophages and other MPs via TGFB2–TGFBR2, TGFB3– TGFBR3, CCL2-CCR1, and CCL2-CCR5 binding (Figure 6B), which play inhibitory roles on the target cells. The gene discussed is TGFB2; the disease is keloid.