Coculture of the human CAR T cells with SKOV3 ovarian tumor cells which are NGcGM3+in vitro (Figure 1G) revealed highest target cell killing by CAR h2 engineered T cells as evaluated in an IncuCyte assay (Figure 1H), but highest IFNγ production by CAR h3 T cells (Figure 1I). This evidence concerns the gene IFNG and ovarian neoplasm.