We also integrated differentially downregulated DEGs from the datasets and identified six downregulated DEGs, namely, MPPED2, TNFRSF11B, FHL1, CRABP1, MATN2, and TFF3, collectively known as thyroid tumor-downregulated genes (TTDGs) (Supplementary Figure S4). The gene discussed is TNFRSF11B; the disease is thyroid tumor.