Similarly, our gene set enrichment analysis (GSEA) demonstrated that thyroid tumor-enriched proteins were significantly enriched in KEGG pathways, including the ABC transporters, transcriptional misregulation in cancer, extracellular matrix (ECM) receptor interaction, proteoglycans in cancer, cell adhesion molecules, and focal adhesion and regulation of the actin cytoskeleton. This evidence concerns the gene ABCG2 and thyroid tumor.