The research has found that in the astrocytes of schizophrenia, the levels of PYGM and RAC1 (a kinase that regulates the activity of PYGM) involved in astrocytes metabolism are reduced, leading to a transient partial energy deficiency in the dorsolateral prefrontal cortex (Pinacho et al., 2016). The gene discussed is PYGM; the disease is schizophrenia.