MMP7 and colorectal carcinoma: Furthermore, a study using CRC-derived cell lines, LoVo and HCT116, found that resveratrol inhibited CRC invasion and metastasis by suppressing Wnt/-catenin signaling and, as a result, the expression of its target genes such as c-Myc, MMP-7, and MALAT1, which leads to the inhibition of CRC invasion and metastasis (331).