Guo et al. demonstrated that genetic polymorphisms of NF-κB pathway, such as CDKN2A rs3088440, CCND1 rs9344, and IKBKB rs12676482, were prone to suffering grade 3/4 acute treatment-induced myelosuppression of NPC patients [23]. The gene discussed is CDKN2A; the disease is nasopharyngeal carcinoma.