Furthermore, the top 10 genes with highest degree of connectivity (ATP5A1, ATP5B, COX5A, GAPDH, NDUFA9, NDUFS3, NDUFV2, SOD1, UQCRC1, and UQCRC2) were identified as hub genes in sleep disorder and AD. The gene discussed is NDUFA9; the disease is Alzheimer disease.