The present study data indicate that symptomatic patients, patients with comorbid conditions (mainly diabetes and hypertension), patients with severe outcomes, and patients with elevated CRP, ferritin, and LDH tend to have a prolonged time of negativization, which was also observed in a Tunisian study [46] and Chinese study [47], where hypertension, diabetes, and disease severity delayed the SARS-CoV-2 virus clearance for extra five days for chronic complications and extra nine days for severe outcomes. The gene discussed is CRP; the disease is diabetes mellitus.