In comparison, trehalose did not affect LPS‐mediated upregulation of CD69 on mouse blood eosinophils and mRNA levels of IL‐5 and IL‐13 in human eosinophilic cell line (Figure S3A,B), suggesting that trehalose may not directly act on eosinophils to alleviate eosinophilia. The gene discussed is IL5; the disease is Increased total eosinophil count.