HSPBP1 (heat shock protein 70-binding protein 1) is a member of the eukaryotic protein family identified as a nucleotide exchange factor for Hsp70 and therefore influences protein quality control [29, 30], which has already been studied in HIV-1, neuropathology, atherosclerosis and other fields [31–33]. This evidence concerns the gene HSPBP1 and atherosclerosis.