The BRCA risk model consisted of 5 AS events, (TTC39C|44853|AT*− 2.67) + (HSPBP1|52052|AP*− 4.28) + (MAZ|35942|ES*2.34) + (ANK3|11845|AP*1.18) + (ZC3HAV1|81940|AT*1.59), which were confirmed to be valuable for predicting BRCA prognosis to a certain degree, including ROC curve, survival analysis, tumor microenvironment analysis, immune infiltration and immune checkpoint analysis. The gene discussed is HSPBP1; the disease is neoplasm.