A breast cancer risk model consisting of 5 AS events was constructed in our study, which was risk score = (TTC39C|44853|AT*− 2.67) + (HSPBP1|52052|AP*− 4.28) + (MAZ|35942|ES*2.34) + (ANK3|11845|AP*1.18) + (ZC3HAV1|81940|AT*1.59). This evidence concerns the gene HSPBP1 and breast carcinoma.