The PGC summary statistics (which include ~37,000 schizophrenia cases, about 65 times the number of cases using SAIGE) uncovered many colocalized loci undetected by using either Neale or SAIGE: for example, genes BNIP3L, CNTN4, THOC7, TRPC4, ZNF823, CLCN3, PAX6 were prioritized in the context of synaptic location and function from genome-wide enrichment tests in the latest PGC schizophrenia meta-analysis27. The gene discussed is TRPC4; the disease is schizophrenia.