POU5F1B and colorectal carcinoma: We validated these results with another publicly available dataset of 18 CRC patients (GSE50760)16, where the LTR66-POU5F1B TcGT was found in 0/18 normal colons, 10/18 primary tumors, and 12/18 liver metastases (Fig. 1a ‘cohort 2’).