POU5F1B and colorectal carcinoma: Downregulating POU5F1B by dox-inducible lentivector-mediated RNA interference impaired the growth of LS1034 (Fig. 2h, Supplementary Fig. 2e), HT55 and LS174T CRC cells (Supplementary Fig. 2f, g), all of which express this TcGT at baseline.