These networks are BRAIN-TEAM with Friedreich ataxia (Rare diseases with motor or cognitive expression of the central nervous system), G2M with Congenital hyperinsulinism and Phenylketonuria (Rare Hereditary Metabolic Diseases), Muco CFTR (Cystic Fibrosis), ORKID with Alport syndrome, Multicystic dysplastic kidney, Haemolytic uremic syndrome (Rare Renal Diseases), and SENSGENE with Bardet Biedl syndrome (Rare sensory diseases). This evidence concerns the gene CFTR and phenylketonuria.