Based on this hypothesis, the specific catalytic scavenger of superoxide15, superoxide dismutase (SOD), which is an enzyme found in most food sources, especially in marine phytoplankton, melons, cruciferous vegetables, is an ideal candidate to alleviate the syndromes of diabetes by reducing the oxidative damage and destruction of the intestinal barrier, thereby ameliorating the vicious circle of hyperglycemia. This evidence concerns the gene SOD1 and diabetes mellitus.