DAO and Alzheimer disease: The DAAO modulator (named pLG72) may affect the DAAO activity (Sacchi et al., 2016; Keller et al., 2018; Lin et al., 2020b) and play important roles in the modulation of NMDA signaling and in the pathogenesis of schizophrenia and AD (Lin et al., 2014b, 2019b, 2020b; Sacchi et al., 2016; Akyol et al., 2017; Keller et al., 2018).