HOXA-AS3 expression was upregulated in several human disorders and pathophysiological processes, such as liver cancer, glioma, lung cancer, oral cancer, colorectal cancer, gastric cancer, pancreatic cancer, endometriosis, atherosclerosis, pulmonary arterial hypertension, and the osteogenic differentiation of MSCs. The gene discussed is HOXA-AS3; the disease is central nervous system cancer.