This was also observed in the CD4+ T cell compartment, with a decrease in the percentage of tumour-infiltrating CD3+CD4+CD27+ post-FLOT chemotherapy compared with the treatment-naïve tissue (16.22 ± 3.6 vs. 4.64 ± 1.8%, p = 0.03), (Fig. 5). This evidence concerns the gene CD27 and neoplasm.