IL2 and neoplasm: OGJ treatment-naïve PBMCs were activated with anti-CD3/28 and IL-2 ex vivo and co-cultured with OE33 cells in the presence of untreated OE33 conditioned media or post-FLOT- and post-CROSS CT-treated OE33 tumour cell conditioned media to determine if the lymphocyte mediated-killing of OE33 cells would be enhanced by the secretome of OE33 cells that had been pre-treated for 48 h with standard of care chemotherapy regimens (Fig. 7).