Hyperinsulinemia resulted in increased phosphorylation of Akt and mTOR with reduced nonphosphorylation of 4E‐BP1 and LC3B‐II, all p < 0.0005, but this effect of insulin was not altered by administration of BHB (see Table 1 and Figure 4). The gene discussed is EIF4EBP1; the disease is Hyperinsulinemia.