A comparison of DNA methylation patterns on leukocyte-derived DNA between patients with metabolic disorders and healthy individuals showed a significant increase in the DNA methylation level of ABCG1 (ATP-binding cassette sub-family G member 1), involved in intracellular and extracellular signaling and lipid transport, in the patient’s DNA compared with that in the DNA of healthy individuals [2]. Here, ABCG1 is linked to metabolic disease.